Five visits. Few side effects.

Prostate cancer is the second most common cancer in men worldwide.1 Today, MRIdian® is changing the paradigm for prostate cancer treatment and may offer patients the ability to treat their cancer with just five fractions and fewer side effects.

Findings published on January 12, 2023, in JAMA Oncology 2 demonstrate the superiority of MRIdian MRI guidance in stereotactic body radiotherapy (SBRT) for localized prostate cancer compared to CT-guided SBRT.

MIRAGE phase III randomized controlled trial (NCT04384770) shows a significant reduction in acute (≤90 days) genitourinary (GU) and gastrointestinal (GI) side effects with MRIdian MRI-guided versus CT-guided SBRT.

On multivariate analysis, which controls for differences in the use of a rectal spacer, prostate size, and baseline urinary symptoms, the MRI-guided arm was associated with a 60% reduction in odds of grade ≥2 GU toxicity.


Better for patients. Better for clinicians. Learn more about MRIdian today.

Learn how MRIdian works for prostate

Prostate Patient Stories

Clinical Resources

To learn more about ongoing clinical trials for prostate cancer, visit our Clinical Trials page.

Where can I go for more information?

Please contact your healthcare provider with any questions or concerns.

Important Safety Information

Indications for Use (IFU): The MRIdian Linac system, with magnetic resonance imaging capabilities, is intended to provide stereotactic radiosurgery and precision radiotherapy for lesions, tumors, and conditions anywhere in the body where radiation treatment is indicated. The MRIdian Linac System is not appropriate for all patients, including those who are not candidates for magnetic resonance imaging.

Important Safety Information (ISI): Radiation treatments may cause side effects that can vary depending on the part of the body being treated. The most frequent ones are typically temporary and may include, but are not limited to, irritation to the respiratory, digestive, urinary or reproductive systems; fatigue; nausea; skin irritation; and hair loss. In some patients, side effects can be severe. Treatment sessions may vary in complexity and duration.

Radiation treatment is not appropriate for all cancers. You should discuss the potential for side effects and their severity as well as the benefits of radiation and magnetic resonance imaging with your doctor to make sure radiation treatment is right for you.

Disclaimer: The opinions and clinical experiences presented herein are specific to the featured physicians and the featured patients and are for information purposes only. Nothing in this material is intended to provide specific medical advice or to take the place of written law or regulations. Results of treatment presented in the videos and information on this webpage are not indicative of typical or future results.

Discuss treatment options with your doctor, including the risks and benefits of the entire course of treatment specific to your individual needs. MRIdian Linac systems are only available at appropriately equipped facilities with specially trained physicians.


  1. Ferlay, J., et al. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. Retrieved August 30, 2019 from (2018)
  2. Kishan AU, Ma TM, Lamb JM, et al. JAMA Oncol. Published online January 12, 2023. doi:10.1001/jamaoncol.2022.6558